Description

Ganglioside Gm3 (Neugc) is a specific glycosphingolipid characterized by the presence of N-glycolylneuraminic acid (NeuGc) instead of the more common N-acetylneuraminic acid (NeuAc). This structural distinction makes it a critical research tool for studying cell membrane biology, immune system modulation, and species-specific biological processes. It is primarily utilized by researchers and developers in the life sciences sector for applications ranging from fundamental biochemical research to the development of diagnostic and therapeutic agents.

Application

• Biomedical Research: Used as a standard or reagent in studies investigating ganglioside function, cell signaling pathways, and membrane receptor interactions.
• Immunology Studies: Serves as an antigen or target in research focused on anti-NeuGc antibodies, xenotransplantation, and understanding immune responses.
• Cancer Research: Employed to explore the role of NeuGc-containing gangliosides in tumor immunology, metastasis, and as potential biomarkers.
• Neurological Research: Applied in models studying neural development, synaptic function, and neurodegenerative diseases where ganglioside profiles are altered.
• Diagnostic Development: Acts as a coating antigen or critical component in the development of immunoassays and biosensors for detecting specific antibodies or ligands.
• Pharmaceutical R&D: Used in drug discovery programs targeting ganglioside-mediated processes, including the design of vaccines and therapeutic antibodies.

Basic Information

Product Name	Ganglioside Gm3 (Neugc)
CAS No.	69345-49-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ganglioside GM3 (NeuGc); II3(NeuGc)-LacCer; N-Glycolylneuraminosyllactosylceramide; NeuGc-GM3; Hematoside (NeuGc); Monosialodihexosylganglioside GM3 (NeuGc); GM3 Ganglioside with N-glycolylneuraminic acid
EINECS	Contact for details

Quality Control

Our Ganglioside Gm3 (Neugc) is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and purity suitable for research applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform/methanol mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.