Description

Piperazine, 1-(8-Chloro-10,11-Dihydro-3-Methoxydibenzo(B,F)Thiepin-10- Yl)-, S-Oxide, (Z)-2-Butenedioate (1:1) is a high-purity pharmaceutical intermediate and active ingredient with a CAS number of 69231-73-8. This compound is critical for ensuring the efficacy and consistency of advanced therapeutic formulations. It is primarily required by pharmaceutical R&D laboratories and manufacturing facilities engaged in the synthesis of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs).
• Neurological & Psychiatric Drug Research: Used in the development of compounds targeting central nervous system (CNS) disorders.
• Preclinical & Clinical Trial Material: Serves as a critical raw material for producing batches for non-clinical and clinical studies.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale manufacturing of new chemical entities.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Custom Synthesis: A starting point for the custom synthesis of novel derivatives for biological screening and patenting.

Basic Information

Product Name	Piperazine, 1-(8-Chloro-10,11-Dihydro-3-Methoxydibenzo(B,F)Thiepin-10- Yl)-, S-Oxide, (Z)-2-Butenedioate (1:1)
CAS No.	69231-73-8
Molecular Formula	C23H25ClN2O5S
Molecular Weight	476.97 g/mol
Synonyms	1-(8-Chloro-10,11-dihydro-3-methoxydibenzo[b,f]thiepin-10-yl)piperazine S-oxide (Z)-2-butenedioate (1:1); Zuclopenthixol Acetate Impurity; Zuclopenthixol Acetate Related Compound; (Z)-1-(8-Chloro-10,11-dihydro-3-methoxydibenzo[b,f]thiepin-10-yl)piperazine 5-oxide maleate; cis-Zuclopenthixol Acetate Impurity; Zuclopenthixol Acetate EP Impurity; Zuclopenthixol Acetate Maleate; 69231-73-8
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(8-Chloro-10,11-Dihydro-3-Methoxydibenzo(B,F)Thiepin-10- Yl)-, S-Oxide, (Z)-2-Butenedioate (1:1) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific pharmacopeial (e.g., USP, EP) or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.