Description

1,2-Cyclopropanedicarbonyl Dichloride, cis- (9Ci) is a highly reactive and versatile acid chloride derivative of cyclopropane-1,2-dicarboxylic acid. This compound is a critical building block in organic synthesis, valued for its strained three-membered ring structure which imparts unique reactivity and stereochemistry to target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, including active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those containing cyclopropane motifs known for metabolic stability and conformational restriction.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the cyclopropane ring enhances biological activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: Utilized in the development of new organic electronic materials and liquid crystals.
• Peptide Mimetics: Acts as a constrained scaffold in the design of peptide analogs to improve bioavailability and receptor selectivity.

Basic Information

Product Name	1,2-Cyclopropanedicarbonyl Dichloride, cis- (9Ci)
CAS No.	69010-17-9
Molecular Formula	C5H4Cl2O2
Molecular Weight	166.99 g/mol
Synonyms	cis-1,2-Cyclopropanedicarbonyl Dichloride; cis-Cyclopropane-1,2-dicarbonyl Dichloride; (1R,2S)-rel-1,2-Cyclopropanedicarbonyl Dichloride; Cyclopropane-1,2-dicarboxylic Acid Dichloride, cis-; 1,2-Cyclopropanedicarboxylic Acid Dichloride; NSC 163082; (1S,2R)-1,2-Cyclopropanedicarbonyl Dichloride
EINECS	Contact for details

Quality Control

Our 1,2-Cyclopropanedicarbonyl Dichloride, cis- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and process chemistry. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. For custom synthesis or specific grade requirements (e.g., anhydrous conditions, higher purity), our technical team can tailor the quality specifications to meet your project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Recommended long-term storage temperature is 2-8°C. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.