Description

(3S)-3Aβ-Bromomethyl-2,3,3A,8B-Tetrahydro-3α,6,8Bβ-Trimethyl-1H-Cyclopenta[B]Benzofuran CAS NO 68773-08-0 is a high-purity, advanced pharmaceutical intermediate characterized by its complex, stereochemically defined cyclopenta[b]benzofuran structure. This compound is of significant value in organic synthesis, serving as a critical chiral building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex, biologically active molecules, particularly in the areas of oncology and inflammation.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and proprietary APIs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective synthesis due to its defined (3S) configuration.
• Process Chemistry Development: Serves as a reference standard and a critical material for scaling up synthetic routes from lab to pilot plant.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	(3S)-3Aβ-Bromomethyl-2,3,3A,8B-Tetrahydro-3α,6,8Bβ-Trimethyl-1H-Cyclopenta[B]Benzofuran
CAS No.	68773-08-0
Molecular Formula	C15H19BrO
Molecular Weight	295.22 g/mol
Synonyms	(3S)-3a-Bromomethyl-2,3,3a,8b-tetrahydro-3a,6,8b-trimethyl-1H-cyclopenta[b]benzofuran; 3a-Bromomethyl-2,3,3a,8b-tetrahydro-3a,6,8b-trimethyl-1H-cyclopenta[b]benzofuran, (3S)-; 1H-Cyclopenta[b]benzofuran, 3a-(bromomethyl)-2,3,3a,8b-tetrahydro-3a,6,8b-trimethyl-, (3S)-; (3S)-3a-(Bromomethyl)-2,3,3a,8b-tetrahydro-3a,6,8b-trimethyl-1H-cyclopenta[b]benzofuran
EINECS	Contact for details

Quality Control

Our (3S)-3Aβ-Bromomethyl-2,3,3A,8B-Tetrahydro-3α,6,8Bβ-Trimethyl-1H-Cyclopenta[B]Benzofuran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.