Description

Loxoprofen is a potent non-steroidal anti-inflammatory drug (NSAID) belonging to the propionic acid derivative class. It is a critical pharmaceutical active ingredient valued for its effective analgesic and anti-inflammatory properties, primarily functioning as a prodrug that is metabolically activated in the body. This compound is essential for manufacturers in the pharmaceutical industry developing prescription and over-the-counter medications for pain and inflammation management.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the key therapeutic component in solid oral dosage forms such as tablets and capsules.
• Analgesic Formulations: Used in medications designed to relieve mild to moderate pain, including musculoskeletal pain and post-operative pain.
• Anti-inflammatory Medications: Incorporated into drugs targeting inflammation associated with conditions like osteoarthritis, rheumatoid arthritis, and tendonitis.
• Antipyretic Drugs: A component in formulations aimed at reducing fever.
• Generic Drug Manufacturing: Serves as the core API for producing generic versions of branded loxoprofen-based medicines.
• Clinical Research & Development: Utilized as a reference standard or raw material in preclinical and clinical studies for new analgesic therapies.

Basic Information

Product Name	Loxoprofen
CAS No.	68767-14-6
Molecular Formula	C15H18O3
Molecular Weight	246.30 g/mol
Synonyms	Loxoprofen Sodium; (±)-2-[4-(2-Oxocyclopentylmethyl)phenyl]propionic Acid; Loxonin; CS-600; Oxoprofen; Loxoprofen (free acid); [p-(2-Oxocyclopentylmethyl)phenyl]propionic Acid
EINECS	Contact for details

Quality Control

Our Loxoprofen is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC. We provide full traceability and support regulatory submissions with comprehensive documentation. Certificates of Analysis (COA) are available upon request, detailing compliance with relevant pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.