Description

(Z)-4-Hydroxy-2-Methyl-2-Butenoic Acid [(3Ar,4R,6E,9S,10Z,11Ar)-9-Acetoxy-2,3,3A,4,5,8,9,11A-Octahydro-6,11-Dimethyl-3-Methylene-2-Oxocyclodeca[B]Furan-4-Yl] Ester is a complex, high-purity chemical ester with a defined stereochemistry, valued for its role as a key synthetic intermediate or reference standard. Its intricate molecular architecture makes it a critical component for advanced research and development in specialized chemical synthesis. This compound is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers developing novel active ingredients and complex natural product derivatives.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of novel drug candidates, particularly in complex macrocyclic or terpenoid-derived structures.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where its unique scaffold can contribute to novel modes of action.
• Fine Chemical Synthesis: Acts as a specialized intermediate for producing high-value, complex molecules used in flavors, fragrances, and advanced material science.
• Natural Product Analog Synthesis: Employed in medicinal chemistry to create analogs of natural products for structure-activity relationship (SAR) studies.
• Reference Standard: Provides an analytical standard for quality control and method development in laboratories analyzing complex organic molecules.
• Academic & Institutional Research: Supports cutting-edge chemical research in universities and institutes focused on synthetic methodology and total synthesis.

Basic Information

Product Name	(Z)-4-Hydroxy-2-Methyl-2-Butenoic Acid [(3Ar,4R,6E,9S,10Z,11Ar)-9-Acetoxy-2,3,3A,4,5,8,9,11A-Octahydro-6,11-Dimethyl-3-Methylene-2-Oxocyclodeca[B]Furan-4-Yl] Ester
CAS No.	68539-58-2
Molecular Formula	C22H30O7
Molecular Weight	406.47 g/mol
Synonyms	4-Hydroxy-2-methyl-2-butenoic acid (3aR,4R,6E,9S,10Z,11aR)-9-(acetyloxy)-2,3,3a,4,5,8,9,11a-octahydro-6,11-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester; (Z)-4-Hydroxy-2-methyl-2-butenoic acid ester with (3aR,4R,6E,9S,10Z,11aR)-9-acetoxy-2,3,3a,4,5,8,9,11a-octahydro-6,11-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-ol; A derivative of Methylenolactocin; Potential macrocyclic lactone intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity essential for sensitive synthetic pathways. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and potential for oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.