Description

14-Fluororetinal is a specialized fluorinated derivative of retinal, a key chromophore in visual pigments. This compound is of significant interest in biochemical and pharmaceutical research for studying the structure and function of rhodopsin and other retinal-binding proteins. It serves as a critical synthetic intermediate and a molecular probe for researchers in photobiology, medicinal chemistry, and vision science. The product is supplied as 14-Fluororetinal CAS NO 68200-23-7 to ensure precise identification and sourcing for global R&D and manufacturing applications.

Application

• Vision Research: As a modified chromophore for probing the mechanism of photoisomerization in rhodopsin and other visual pigments.
• Medicinal Chemistry: A key synthetic intermediate in the development of novel retinoid-based therapeutics and drug candidates.
• Biochemical Probes: Used to study protein-ligand interactions, receptor activation, and signal transduction pathways involving retinoid receptors.
• Photobiology Studies: Employed in research on light-sensitive biological systems and the engineering of novel photoreceptive proteins.
• Advanced Material Synthesis: A building block for creating specialized organic molecules and materials with unique photophysical properties.

Basic Information

Product Name	14-Fluororetinal
CAS No.	68200-23-7
Molecular Formula	C20H27FO
Molecular Weight	302.43 g/mol
Synonyms	14-Fluoro-retinal; (all-E)-14-Fluororetinal; 14-Fluoro-11-cis-retinal (if applicable); 14-Fluororetinaldehyde; 14-F-Retinal; Retinal, 14-fluoro-; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-14-fluoronona-2,4,6,8-tetraenal
EINECS	Contact for details

Quality Control

Our 14-Fluororetinal is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at recommended temperatures between -20°C to -10°C to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline solid or powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95% (Typical 97-99%)
Isomeric Purity	Specified per grade (e.g., all-E or 11-cis)
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.