Description

1-O,2-o-Dioleoyl-3-o-Acetyl-Sn-Glycerol is a structured triacylglycerol (TAG) derivative, specifically an acetylated diglyceride. This compound is significant as a versatile synthetic intermediate and a model lipid for research into lipid metabolism, digestion, and absorption. It is primarily needed by manufacturers and researchers in the pharmaceutical, nutraceutical, and specialty chemical industries for applications in drug delivery systems, lipid-based formulations, and biochemical studies.

Application

• Pharmaceutical Excipient: Used as a lipid component in the development of self-emulsifying drug delivery systems (SEDDS) and other lipid-based formulations to enhance the bioavailability of poorly water-soluble drugs.
• Biochemical Research: Serves as a critical substrate or standard in enzymatic studies, particularly for investigating the activity of lipases, phospholipases, and other lipid-metabolizing enzymes.
• Nutraceutical Intermediate: Acts as a precursor or structured lipid in the synthesis of specialized nutritional oils and bioactive lipid compounds designed for targeted metabolic effects.
• Cosmetic Formulations: Employed as an emollient and skin-conditioning agent in high-end cosmetic and dermatological preparations due to its skin-compatible lipid structure.
• Synthetic Chemistry Building Block: Utilized as a key intermediate in organic synthesis for the preparation of more complex glycerolipids, phospholipid analogs, and other bioactive molecules.
• Analytical Reference Standard: Provides a high-purity standard for chromatographic analysis (HPLC, GC) and mass spectrometry in quality control and research laboratories.

Basic Information

Product Name	1-O,2-o-Dioleoyl-3-o-Acetyl-Sn-Glycerol
CAS No.	67873-96-5
Molecular Formula	C41H74O6
Molecular Weight	663.03 g/mol
Synonyms	1,2-Dioleoyl-3-acetyl-rac-glycerol; 3-Acetyl-1,2-dioleoylglycerol; Acetyl diolein; 1,2-Dioleoyl-3-acetylglycerol; sn-3-Acetyl-1,2-dioleoylglycerol; TAG 18:1/18:1/2:0; Glycerol 1,2-dioleate 3-acetate
EINECS	Contact for details

Quality Control

Our 1-O,2-o-Dioleoyl-3-o-Acetyl-Sn-Glycerol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods, to ensure high purity and consistent composition. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and hydrolysis. For long-term storage, keep the material frozen at -20°C or below. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous oil
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Acid Value	≤ 2.0 mg KOH/g
Peroxide Value	≤ 5.0 meq/kg
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.