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Dibenzyl Diethylphosphoramidite CAS NO 67746-43-4


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CAS No.:67746-43-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dibenzyl Diethylphosphoramidite is a specialized organophosphorus compound widely used as a key ligand and reagent in advanced chemical synthesis. Its primary value lies in its role as a highly effective catalyst precursor and chiral auxiliary in asymmetric transformations, particularly in the pharmaceutical and agrochemical sectors. This product is essential for researchers and manufacturers in fine chemical synthesis, catalyst development, and the production of active pharmaceutical ingredients (APIs) requiring precise stereochemical control.

Application

  • Catalyst Ligand in Asymmetric Synthesis: A crucial component for creating chiral catalysts used in hydrogenation, hydroformylation, and other enantioselective reactions.
  • Pharmaceutical Intermediate Manufacturing: Used in the synthesis of complex, stereochemically-defined drug molecules and active pharmaceutical ingredients (APIs).
  • Agrochemical Production: Employed in the development of chiral pesticides and herbicides where specific isomer activity is required.
  • Material Science Research: Serves as a building block or modifying agent in the development of novel polymers and functional materials.
  • Academic & Industrial R&D: A valuable reagent for methodological development in organic and organometallic chemistry laboratories.

Basic Information

Product Name Dibenzyl Diethylphosphoramidite
CAS No. 67746-43-4
Molecular Formula C₁₈H₂₄NO₂P
Molecular Weight 317.36 g/mol
Synonyms Diethyl (Dibenzylamino)phosphonite; Phosphorous Acid, P,P-Diethyl P',P'-Bis(phenylmethyl) Ester Diamide; N,N-Dibenzyl-P,P-diethylphosphinous Amide; Dibenzylamino-diethoxyphosphine; Diethyl Dibenzylphosphoramidite; BDBPA; DBDPA
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Quality Control

Our Dibenzyl Diethylphosphoramidite is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including NMR (¹H, ³¹P), HPLC, and Karl Fischer titration, to confirm identity, potency, and the absence of critical impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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