Description

(6S)-3-[(Z)-[2-(3-Methyl-2-Butenyl)-1H-Imidazol-4-Yl]Methylene]-6α-(1-Methylethyl)Piperazine-2,5-Dione is a specialized heterocyclic compound featuring a unique piperazinedione core fused with an imidazole moiety. This complex molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Protease Inhibitor Development: The piperazine-2,5-dione structure is relevant for designing inhibitors of specific enzymes.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological processes and protein interactions.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Academic Research: Employed in university and institutional labs for synthetic methodology development and bioorganic chemistry studies.

Basic Information

Product Name	(6S)-3-[(Z)-[2-(3-Methyl-2-Butenyl)-1H-Imidazol-4-Yl]Methylene]-6α-(1-Methylethyl)Piperazine-2,5-Dione
CAS No.	67603-38-7
Molecular Formula	C17H24N4O2
Molecular Weight	316.40 g/mol
Synonyms	(6S)-3-[(Z)-[2-(3-Methylbut-2-en-1-yl)-1H-imidazol-4-yl]methylene]-6-(propan-2-yl)piperazine-2,5-dione; 6α-Isopropyl-3-[(Z)-[2-(3-methyl-2-butenyl)-1H-imidazol-4-yl]methylene]piperazine-2,5-dione; (S)-3-((Z)-((2-(3-Methylbut-2-en-1-yl)-1H-imidazol-4-yl)methylene)-6-isopropylpiperazine-2,5-dione; 67603-38-7; UNII-9F2C9S9Q8J; 9F2C9S9Q8J
EINECS	Contact for details

Quality Control

Our production of (6S)-3-[(Z)-[2-(3-Methyl-2-Butenyl)-1H-Imidazol-4-Yl]Methylene]-6α-(1-Methylethyl)Piperazine-2,5-Dione adheres to stringent quality protocols suitable for GMP-grade intermediates. Every batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis to confirm stereochemical integrity, and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.