Description

n-Heptadecanoyl-D-Erythro-Sphingosine is a high-purity, synthetic sphingolipid derivative, a critical building block for advanced biochemical research and pharmaceutical development. Its value lies in its role as a precisely defined standard and precursor for studying cell membrane structure, signaling pathways, and lipid metabolism. This compound is essential for researchers and manufacturers in the life sciences, particularly those developing novel therapeutics, diagnostic tools, and specialized lipid-based delivery systems.

Application

• Biochemical Research Standard: Used as a certified reference material for the quantification and characterization of complex sphingolipids in analytical methods like LC-MS and HPLC.
• Pharmaceutical Intermediates: Serves as a key synthetic precursor in the development of novel drug candidates targeting sphingolipid-related diseases, such as cancer, inflammation, and metabolic disorders.
• Lipidomics Studies: A vital tool for investigating lipid raft composition, cell signaling cascades (e.g., ceramide-mediated apoptosis), and metabolic flux in lipid pathways.
• Cell Culture & Media Supplement: Employed in specialized cell culture applications to study the effects of specific sphingolipids on cell growth, differentiation, and function.
• Cosmeceutical R&D: Investigated for potential applications in advanced skincare formulations aimed at modulating skin barrier function and cellular communication.
• Enzyme Substrate: Acts as a substrate for enzymes like ceramidases and sphingomyelin synthases in enzymatic activity assays and inhibitor screening.

Basic Information

Product Name	n-Heptadecanoyl-D-Erythro-Sphingosine
CAS No.	67492-16-4
Molecular Formula	C35H69NO3
Molecular Weight	551.93 g/mol
Synonyms	N-Heptadecanoylsphingosine; D-erythro-Sphingosine, N-heptadecanoyl-; Ceramide (d18:1/17:0); N-(Heptadecanoyl)-D-erythro-sphingosine; N-Heptadecanoyl-D-erythro-sphingosine; C17-Ceramide (d18:1); Heptadecanoyl sphingosine; N-Margaroylsphingosine
EINECS	Contact for details

Quality Control

Our n-Heptadecanoyl-D-Erythro-Sphingosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.