Description

1,3-Dipalmitoyl-Glycero-2-Phosphoethanolamine is a high-purity synthetic phospholipid, specifically a phosphatidylethanolamine (PE), that serves as a critical building block for advanced lipid-based formulations. Its value lies in its defined chemical structure, which provides superior batch-to-batch consistency for research and manufacturing processes requiring precise molecular composition. This compound is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who are developing liposomal drug delivery systems, lipid nanoparticles (LNPs), and synthetic cell membrane models.

Application

• Liposomal Drug Delivery: A key structural lipid for creating stable, biocompatible liposomes to encapsulate and deliver therapeutic agents.
• mRNA Vaccine & Therapeutic Platforms: Used as a helper lipid or structural component in lipid nanoparticle (LNP) formulations for nucleic acid delivery.
• Biomimetic Membrane Research: Essential for constructing synthetic bilayers and vesicles to study membrane biophysics, protein-lipid interactions, and cellular processes.
• Diagnostic Reagents: Incorporated into lipid-based assays and sensors for enhanced specificity and performance.
• Cosmetic & Dermal Formulations: Employed in high-end cosmetic products as a skin-identical lipid to improve barrier function and delivery of active ingredients.
• Bioconjugation & Labeling: Serves as a substrate for chemical modification due to its reactive primary amine group, enabling attachment of probes, tags, or targeting ligands.

Basic Information

Product Name	1,3-Dipalmitoyl-Glycero-2-Phosphoethanolamine
CAS No.	67303-93-9
Molecular Formula	C37H74NO8P
Molecular Weight	691.96 g/mol
Synonyms	DPPE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine; Dipalmitoylphosphatidylethanolamine; Phosphatidylethanolamine (16:0/16:0); PE(16:0/16:0); L-α-Phosphatidylethanolamine, dipalmitoyl; 1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine; (R)-2,3-Bis(hexadecanoyloxy)propyl (2-aminoethyl) phosphate
EINECS	Contact for details

Quality Control

Our 1,3-Dipalmitoyl-Glycero-2-Phosphoethanolamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 10 ppm
Solvent Residues	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.