Description

Piperidine, 4-[4-(Trifluoromethyl)Phenyl]- is a specialized piperidine derivative featuring a trifluoromethylphenyl substituent, a structural motif of significant interest in advanced organic synthesis. This compound matters as a versatile and high-value pharmaceutical intermediate and building block for the development of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the biological activity of the piperidine scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of advanced organic materials, including liquid crystals and polymers with specific electronic properties.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated piperidine architectures.

Basic Information

Product Name	Piperidine, 4-[4-(Trifluoromethyl)Phenyl]-
CAS No.	67259-63-6
Molecular Formula	C12H14F3N
Molecular Weight	229.24 g/mol
Synonyms	4-[4-(Trifluoromethyl)phenyl]piperidine; 4-(4-Trifluoromethylphenyl)piperidine; 1-(4-Trifluoromethylphenyl)piperidin-4-amine (tautomer); 4-(α,α,α-Trifluoro-p-tolyl)piperidine; 4-(4-Trifluoromethylphenyl)piperidine; 4-(p-Trifluoromethylphenyl)piperidine; 67259-63-6; AURORA KA-7531
EINECS	Contact for details

Quality Control

Our Piperidine, 4-[4-(Trifluoromethyl)Phenyl]- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP for pharmaceutical intermediates and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.