Description

2-Chloro-6-(1-Piperazinyl)-Pyrazine Hydrochloride is a high-purity pharmaceutical intermediate and research chemical of significant synthetic utility. Its core value lies in its role as a key building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• API Synthesis: Serves as a key building block for the development and scale-up of novel Active Pharmaceutical Ingredients (APIs).
• Chemical Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and creating libraries of compounds for biological screening.
• Agrochemical Research: Employed in the development of new pesticides and herbicides due to its heterocyclic structure.
• Ligand Synthesis: Useful in the preparation of specialized ligands for catalysis and material science applications.

Basic Information

Product Name	2-Chloro-6-(1-Piperazinyl)-Pyrazine Hydrochloride
CAS No.	67250-10-6
Molecular Formula	C8H12ClN5•HCl
Molecular Weight	266.58 g/mol
Synonyms	2-Chloro-6-piperazin-1-ylpyrazine Hydrochloride; 2-Chloro-6-(piperazin-1-yl)pyrazine Hydrochloride; 6-Chloro-3-piperazin-1-ylpyrazine Hydrochloride; 2-Chloro-6-piperazinylpyrazine Hydrochloride; 2-Chloro-6-(1-piperazinyl)pyrazine Monohydrochloride; 67250-10-6 (CAS); 2-Chloro-6-piperazin-1-yl-pyrazine HCl
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(1-Piperazinyl)-Pyrazine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation upon exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.