Description

10,11-Dihydro-5-(3-Piperidinopropylidene)-5H-Dibenzo[A,D]Cycloheptene is a high-purity, advanced pharmaceutical intermediate characterized by its complex tricyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical industry for the development and production of central nervous system (CNS) targeting drugs. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel therapeutic agents, particularly those targeting neurological pathways.
• Research & Development: Used in academic and industrial laboratories for pharmacological studies, structure-activity relationship (SAR) exploration, and new drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: A key structural component in the manufacturing process of specific, proprietary CNS-active pharmaceuticals.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	10,11-Dihydro-5-(3-Piperidinopropylidene)-5H-Dibenzo[A,D]Cycloheptene
CAS No.	67195-19-1
Molecular Formula	C23H27N
Molecular Weight	317.47 g/mol
Synonyms	5-(3-Piperidinopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene; 10,11-Dihydro-5-(3-piperidin-1-yl-propylidene)-5H-dibenzo[a,d]cycloheptene; Pizotifen Intermediate; Sandomigran Intermediate; BC-105 Intermediate; Pizotyline Intermediate; 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-(piperidin-1-yl)propane
EINECS	Contact for details

Quality Control

Every batch of 10,11-Dihydro-5-(3-Piperidinopropylidene)-5H-Dibenzo[A,D]Cycloheptene is manufactured and tested under strict quality management systems. We ensure compliance with current industry standards for pharmaceutical intermediates. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee specification adherence and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.