Description

3-Morpholin-4-Ylpyrazine-2-Carbonitrile is a high-value heterocyclic building block featuring a pyrazine core substituted with a morpholine ring and a nitrile functional group. This compound is critical for medicinal chemistry research and pharmaceutical development, serving as a versatile intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to introduce specific pharmacophores into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of potential drug candidates, particularly for kinase inhibitors and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides and fungicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes and enzyme inhibitors to study biological pathways.
• Material Science Research: Investigated as a precursor for the synthesis of organic semiconductors and ligands for catalytic complexes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.
• Academic Research: Utilized in university and institutional laboratories for methodological development and novel heterocyclic chemistry exploration.

Basic Information

Product Name	3-Morpholin-4-Ylpyrazine-2-Carbonitrile
CAS No.	67130-86-3
Molecular Formula	C9H10N4O
Molecular Weight	190.20 g/mol
Synonyms	3-(4-Morpholinyl)-2-pyrazinecarbonitrile; 3-Morpholin-4-ylpyrazine-2-carbonitrile; 2-Pyrazinecarbonitrile, 3-(4-morpholinyl)-; 3-Morpholinopyrazine-2-carbonitrile; 3-(Morpholin-4-yl)pyrazine-2-carbonitrile; 4-(2-Cyanopyrazin-3-yl)morpholine; 3-Morpholin-4-yl-pyrazine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Morpholin-4-Ylpyrazine-2-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our standard is to supply material with a typical purity of ≥97% (HPLC), with higher grades available upon request to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.