Description

2,5-Piperazinedione, 3-[(1R)-1-Hydroxyethyl]-, (3S)- (9Ci) is a high-purity chiral piperazinedione derivative, a key advanced intermediate in modern pharmaceutical synthesis. Its precise stereochemistry makes it an invaluable building block for creating complex, biologically active molecules with high enantiomeric purity. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutics, including enzyme inhibitors and peptide mimetics.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for complex drug candidates.
• Peptidomimetic Research: Serves as a constrained scaffold or building block in the design and synthesis of peptidomimetics and protease inhibitors.
• Asymmetric Synthesis: Utilized in stereoselective chemical reactions to introduce specific chiral centers into target molecules.
• Medicinal Chemistry: Employed in lead optimization and structure-activity relationship (SAR) studies during drug discovery programs.
• Bioconjugation Chemistry: Potential use in creating linkers or functionalized platforms for bioconjugation applications.
• Academic & Industrial R&D: Used in chemical research for developing new synthetic methodologies and exploring novel chemical entities.

Basic Information

Product Name	2,5-Piperazinedione, 3-[(1R)-1-Hydroxyethyl]-, (3S)- (9Ci)
CAS No.	67106-24-5
Molecular Formula	C6H10N2O3
Molecular Weight	158.16 g/mol
Synonyms	(3S)-3-[(1R)-1-Hydroxyethyl]piperazine-2,5-dione; (S)-3-[(R)-1-Hydroxyethyl]-2,5-piperazinedione; L-(+)-Alanyl-D-lactic acid intramolecular amide; Alanyl lactate diketopiperazine; 3-[(1R)-1-Hydroxyethyl]-2,5-diketopiperazine (3S)-; Cyclo(L-alanyl-D-lactyl); DKP derivative of alanine and lactic acid
EINECS	Contact for details

Quality Control

Every batch of 2,5-Piperazinedione, 3-[(1R)-1-Hydroxyethyl]-, (3S)- (9Ci) is manufactured under strict quality management protocols. We employ advanced analytical techniques, including HPLC, GC, and chiral analysis, to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.