Description

(3R)-3Aα,4,4Aβ,5,6,7,8,8A,9,9Aα-Decahydro-3α,8Aα-Dimethyl-5-Methylenenaphtho[2,3-B]Furan-2(3H)-One is a high-purity, complex sesquiterpene lactone derivative with a defined stereochemistry. This compound serves as a critical advanced intermediate or reference standard in sophisticated organic synthesis and pharmaceutical research. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and studying structure-activity relationships.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of complex natural product analogs and potential therapeutic agents.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in regulatory filings.
• Agrochemical Research: Intermediate in the development of new bioactive compounds with herbicidal or pesticidal activity.
• Organic Synthesis: Versatile starting material for exploring novel chemical transformations and constructing intricate molecular architectures.
• Academic & Institutional Research: Used in universities and research institutes for studies in medicinal chemistry, total synthesis, and chemical biology.
• Flavor & Fragrance Precursor: Potential intermediate for synthesizing specific sesquiterpenoid components used in high-value fragrance compositions.

Basic Information

Product Name	(3R)-3Aα,4,4Aβ,5,6,7,8,8A,9,9Aα-Decahydro-3α,8Aα-Dimethyl-5-Methylenenaphtho[2,3-B]Furan-2(3H)-One
CAS No.	66964-61-2
Molecular Formula	C₁₅H₂₀O₂
Molecular Weight	232.32 g/mol
Synonyms	(3R)-3aα,4,4aβ,5,6,7,8,8a,9,9aα-Decahydro-3aα,8aα-dimethyl-5-methylenenaphtho[2,3-b]furan-2(3H)-one; (3R)-3a,4,4a,5,6,7,8,8a,9,9a-Decahydro-3a,8a-dimethyl-5-methylenenaphtho[2,3-b]furan-2(3H)-one; 5-Methylene-3a,8a-dimethyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydronaphtho[2,3-b]furan-2(3H)-one; A sesquiterpene lactone derivative.
EINECS	Contact for details

Quality Control

Every batch of our (3R)-3Aα,4,4Aβ,5,6,7,8,8A,9,9Aα-Decahydro-3α,8Aα-Dimethyl-5-Methylenenaphtho[2,3-B]Furan-2(3H)-One is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory and research needs. A detailed Certificate of Analysis (COA) including results for assay, chiral purity, and related substances is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.