Description

2-Palmitoyl-Sn-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid, specifically a lysophosphatidylcholine (LPC), that serves as a critical building block and functional excipient in advanced formulations. Its precise structure is essential for creating stable lipid bilayers and vesicles, making it invaluable for research and development in cutting-edge delivery systems. This compound is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and advanced cosmetics industries.

Application

• Liposome and Nanoparticle Formulation: A key structural component for creating unilamellar vesicles used in drug delivery systems for targeted cancer therapies, mRNA vaccines, and other biologics.
• Biomembrane Research: Used as a standard or model lipid in biophysical studies to investigate membrane fluidity, permeability, and protein-lipid interactions.
• Cell Culture & Transfection: Employed as an excipient in transfection reagents to enhance the efficiency of nucleic acid delivery into cells in vitro.
• Pharmaceutical Excipient: Functions as a solubilizer and emulsifying agent in injectable formulations to improve the stability and bioavailability of poorly soluble active pharmaceutical ingredients (APIs).
• Cosmetic Actives Carrier: Utilized in high-end cosmetic products to encapsulate and facilitate the dermal delivery of vitamins, antioxidants, and other active compounds.
• Diagnostic Reagent Preparation: Serves as a raw material in the manufacture of specific diagnostic kits and assays that involve lipid-based detection mechanisms.

Basic Information

Product Name	2-Palmitoyl-Sn-Glycero-3-Phosphocholine
CAS No.	66757-27-5
Molecular Formula	C24H50NO7P
Molecular Weight	495.63 g/mol
Synonyms	1-Hexadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine; 16:0 Lyso PC; Lyso-PC 16:0; Palmitoyl Lysophosphatidylcholine; LPC(16:0/0:0); 1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine; sn-Glycero-3-phosphocholine, 1-palmitoyl-; Lysophosphatidylcholine 16:0
EINECS	Contact for details

Quality Control

Our 2-Palmitoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, methanol; forms micelles in water
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 10 ppm
Bacterial Endotoxins	< 0.5 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.