Description

Ketorolac Isopropyl Ester is a key pharmaceutical intermediate in the synthesis of the potent non-steroidal anti-inflammatory drug (NSAID), Ketorolac Tromethamine. This compound matters for its critical role in ensuring the purity, efficacy, and regulatory compliance of the final active pharmaceutical ingredient (API). It is primarily needed by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers engaged in the production of analgesic and anti-inflammatory medications.

Application

• Primary Intermediate in the synthesis of Ketorolac Tromethamine API.
• Pharmaceutical Research & Development for novel NSAID formulations and prodrug studies.
• Process Chemistry optimization and scale-up in GMP manufacturing facilities.
• Reference Standard for analytical method development and quality control testing.
• Fine Chemical Synthesis for creating specialized derivatives with targeted therapeutic profiles.

Basic Information

Item	Detail
Product Name	Ketorolac Isopropyl Ester
CAS No.	66635-74-3
Molecular Formula	C19H24N2O4
Molecular Weight	344.41 g/mol
Synonyms	Isopropyl 5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate; (±)-5-Benzoyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic Acid 1-Methylethyl Ester; Ketorolac Isopropyl Ester; Ketorolac Isopropylester; Ketorolac Isopropyl Ester Intermediate; Ketorolac Ester; RS-37619 (Isopropyl Ester)
EINECS	Contact for details

Quality Control

Our Ketorolac Isopropyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.