Description

α-[(4-Chlorophenoxy)Methyl]-4-(o-Tolyl)-1-Piperazineethanol is a high-purity, synthetically derived piperazine derivative with a complex molecular architecture. This compound serves as a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential central nervous system (CNS) active compounds and receptor modulators.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Preclinical Development: Employed in the scale-up synthesis of compounds for pharmacological and toxicological evaluation.
• Custom Synthesis: Starting material for the contract manufacturing of specialized, non-commercial fine chemicals and proprietary molecules.

Basic Information

Product Name	α-[(4-Chlorophenoxy)Methyl]-4-(o-Tolyl)-1-Piperazineethanol
CAS No.	66307-61-7
Molecular Formula	C20H25ClN2O2
Molecular Weight	360.88 g/mol
Synonyms	1-Piperazineethanol, α-[(4-chlorophenoxy)methyl]-4-(2-methylphenyl)-; 4-(2-Methylphenyl)-α-[(4-chlorophenoxy)methyl]-1-piperazineethanol; 2-[(4-(2-Methylphenyl)piperazin-1-yl]-(4-chlorophenoxy)ethanol; (RS)-2-[4-(2-Methylphenyl)piperazin-1-yl]-1-(4-chlorophenoxy)ethanol; Contact for additional trade names and identifiers.
EINECS	Contact for details

Quality Control

Our α-[(4-Chlorophenoxy)Methyl]-4-(o-Tolyl)-1-Piperazineethanol is manufactured under a strict quality management system. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting specifications for research and development use. A detailed Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.