Description

α-(Phenoxymethyl)-4-(3-Methoxyphenyl)-1-Piperazineethanol CAS NO 66307-55-9 is a high-purity, synthetic organic compound belonging to the piperazineethanol class of fine chemicals. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and contract manufacturing organizations (CMOs) engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential central nervous system (CNS) active drugs and receptor modulators.
• Research Chemical: Used in academic and industrial research for studying structure-activity relationships (SAR) and developing new pharmacophores.
• Precursor for Active Pharmaceutical Ingredients (APIs): Serves as a core structural component in the multi-step synthesis of candidate drug molecules.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Process Chemistry Development: Utilized in optimizing scalable synthetic routes for potential new chemical entities (NCEs).

Basic Information

Product Name	α-(Phenoxymethyl)-4-(3-Methoxyphenyl)-1-Piperazineethanol
CAS No.	66307-55-9
Molecular Formula	C20H26N2O3
Molecular Weight	342.44 g/mol
Synonyms	1-[2-Hydroxy-2-(4-(3-methoxyphenyl)-1-piperazinyl)ethyl]phenoxymethane; 4-(3-Methoxyphenyl)-α-(phenoxymethyl)-1-piperazineethanol; 1-Piperazineethanol, α-(phenoxymethyl)-4-(3-methoxyphenyl)-; Phenoxymethyl-4-(3-methoxyphenyl)piperazineethanol; CAS 66307-55-9
EINECS	Contact for details

Quality Control

Our α-(Phenoxymethyl)-4-(3-Methoxyphenyl)-1-Piperazineethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically ≥97% by HPLC), residual solvents, and related substances are provided and available upon request. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.