Description

α-Benzyl-4-Phenyl-1-Piperazineethanol CAS NO 66307-51-5 is a specialized piperazine derivative with a distinct molecular structure featuring benzyl and phenyl substituents. This compound is valued as a crucial synthetic intermediate in advanced organic synthesis, particularly for constructing complex nitrogen-containing heterocycles. It is primarily sought by research institutions and pharmaceutical development companies engaged in medicinal chemistry and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new pharmacophores with modified biological activity.
• Organic Synthesis: Serves as a versatile precursor for the preparation of more complex piperazine-based compounds and fine chemicals.
• Biochemical Research: Potential use as a ligand or probe in biochemical assays studying receptor interactions.
• Academic Research: Employed in university and institutional labs for methodological development and novel synthetic route exploration.

Basic Information

Product Name	α-Benzyl-4-Phenyl-1-Piperazineethanol
CAS No.	66307-51-5
Molecular Formula	C19H24N2O
Molecular Weight	296.41 g/mol
Synonyms	α-Benzyl-4-phenyl-1-piperazineethanol; 1-Piperazineethanol, α-(phenylmethyl)-4-phenyl-; 2-[(4-Phenyl-1-piperazinyl)(phenyl)methyl]ethanol; (RS)-2-[(4-Phenylpiperazin-1-yl)(phenyl)methyl]ethanol; (±)-2-[(4-Phenyl-1-piperazinyl)(phenyl)methyl]ethanol
EINECS	Contact for details

Quality Control

Our α-Benzyl-4-Phenyl-1-Piperazineethanol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP standards for pharmaceutical intermediate applications, and our quality protocols are designed to meet the rigorous demands of research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.