Description

1-(2-Fluorophenyl)Biguanide Hydrochloride is a high-purity, synthetically derived biguanide derivative, serving as a critical pharmaceutical intermediate. Its core value lies in its role as a key building block for the development of novel therapeutic agents, particularly in metabolic and antimicrobial research. This compound is essential for R&D chemists and manufacturers in the pharmaceutical and life sciences industries who require reliable, high-quality intermediates for drug discovery and process development. Consistent quality and supply chain integrity are paramount for its successful application in advanced synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel biguanide-based drug candidates, particularly for metabolic disorders.
• Antimicrobial Research: Used in the development and study of new compounds with potential antibacterial or antifungal properties.
• Chemical Synthesis Building Block: Employed in organic synthesis to introduce the 1-(2-fluorophenyl)biguanide moiety into more complex molecular architectures.
• Biochemical Research: Utilized in life science research to investigate enzyme inhibition and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	1-(2-Fluorophenyl)Biguanide Hydrochloride
CAS No.	66088-51-5
Molecular Formula	C8H10FN5·HCl
Molecular Weight	231.65 g/mol
Synonyms	1-(2-Fluorophenyl)biguanide monohydrochloride; N-(2-Fluorophenyl)imidodicarbonimidic diamide hydrochloride; 2-Fluorophenylbiguanide hydrochloride; (2-Fluorophenyl)guanidine, N-cyano- hydrochloride; Biguanide, 1-(2-fluorophenyl)-, monohydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorophenyl)Biguanide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.