Description

4,4'-(1,2-Cyclopropanediyl)Bis(2,6-Piperazinedione) is a specialized heterocyclic compound featuring a unique cyclopropane-bridged bis-piperazinedione structure. This molecular architecture makes it a valuable high-purity intermediate and building block for advanced pharmaceutical research and fine chemical synthesis. It is primarily sought by research institutions and pharmaceutical developers working on novel active pharmaceutical ingredients (APIs), particularly in areas requiring complex, constrained molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, especially those targeting neurological or oncological pathways.
• Chemical Research & Development: Used as a building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Advanced Material Synthesis: Potential application in creating novel polymers or ligands with specific steric and electronic properties.
• Academic Research: Employed in universities and research institutes for studying cyclopropane chemistry and heterocyclic compound reactivity.
• Process Development: Used in scaling up synthetic routes for pilot-scale and commercial manufacturing of specialty chemicals.

Basic Information

Product Name	4,4'-(1,2-Cyclopropanediyl)Bis(2,6-Piperazinedione)
CAS No.	66054-21-5
Molecular Formula	C13H18N4O4
Molecular Weight	294.31 g/mol
Synonyms	1,1'-(1,2-Cyclopropanediyl)bis[hexahydro-2,6-dioxo-4-pyrazinecarboxylic acid]; Cyclopropane-1,2-diylbis(hexahydro-2,6-dioxo-4-pyrazinecarboxylic acid); 4,4'-(Cyclopropane-1,2-diyl)bis(hexahydro-2,6-dioxopyrazine-1(2H)-carboxylic acid); 1,1'-Cyclopropanediylbis[hexahydro-2,6-dioxo-4-pyrazinecarboxylic acid]; Bis-piperazinedione cyclopropane derivative
EINECS	Contact for details

Quality Control

Our 4,4'-(1,2-Cyclopropanediyl)Bis(2,6-Piperazinedione) is produced under a strict quality management system. Every batch undergoes rigorous analytical testing including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.