Description

Chaetoglobosinj is a complex secondary metabolite belonging to the cytochalasan family of fungal mycotoxins. This compound is of significant interest in biochemical and pharmacological research due to its potent biological activity, particularly as an inhibitor of actin polymerization and microtubule assembly. It serves as a critical reference standard and research tool for scientists in the fields of cell biology, toxicology, and natural product chemistry, enabling the study of cytoskeletal dynamics and cellular morphology.

Application

• Biochemical Research: Used as a potent and specific inhibitor of actin polymerization in studies of cytoskeletal dynamics and cell motility.
• Pharmacological Studies: Employed as a reference compound to investigate cytotoxic mechanisms, apoptosis induction, and potential anti-cancer activities.
• Mycotoxin Analysis: Serves as a certified analytical standard for the detection and quantification of chaetoglobosins in food, feed, and environmental samples.
• Cell Biology Tool: Applied in cellular assays to disrupt microfilament networks, aiding in the study of cell division, shape, and intracellular transport.
• Natural Product Chemistry: Used as a reference for the isolation, structural elucidation, and synthesis of related cytochalasan alkaloids.
• Quality Control & Method Development: Essential for developing and validating analytical methods (HPLC, LC-MS) in pharmaceutical and agrochemical quality control laboratories.

Basic Information

Product Name	Chaetoglobosinj
CAS No.	65745-47-3
Molecular Formula	C34H39NO7
Molecular Weight	573.68 g/mol
Synonyms	Chaetoglobosin J; Chaetoglobosin-J; 19-O-Acetylchaetoglobosin A; Cytochalasin J; NSC 332836; (1S,7S,13E,15E,18S,21R)-18-(Acetyloxy)-1,21-dihydroxy-12-(1-hydroxyethyl)-11-methyl-8-oxo-17-oxa-12-azatricyclo[17.3.1.0²,⁷]tricosa-2,4,6,13,15,19-hexaene-4,10-dicarbonitrile
EINECS	Contact for details

Quality Control

Our Chaetoglobosinj is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analysis using advanced techniques including HPLC, NMR, and MS for identity confirmation and purity assessment. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.