Description

2-(3,4,5-Trimethoxy-Phenyl)-Piperazine is a high-purity, specialized organic compound belonging to the piperazine class, characterized by its trimethoxyphenyl substituent. This structural motif makes it a valuable key intermediate and building block for the synthesis of more complex molecules in advanced research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular systems.
• Chemical Research & Development: Used as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of complex APIs where the piperazine core is a required pharmacophore.
• Reference Standard: Supplied as a high-purity compound for analytical testing, method development, and quality control in regulatory submissions.
• Fine Chemical Production: Acts as a key intermediate in the manufacture of specialty chemicals for agrochemical and material science applications.

Basic Information

Product Name	2-(3,4,5-Trimethoxy-Phenyl)-Piperazine
CAS No.	65709-47-9
Molecular Formula	C13H20N2O3
Molecular Weight	252.31 g/mol
Synonyms	1-(3,4,5-Trimethoxyphenyl)piperazine; 2-(3,4,5-Trimethoxyphenyl)piperazine; 3,4,5-Trimethoxyphenylpiperazine; 65709-47-9; 1-Piperazine, 1-(3,4,5-trimethoxyphenyl)-; 3,4,5-Trimethoxybenzenepiperazine
EINECS	Contact for details

Quality Control

Our 2-(3,4,5-Trimethoxy-Phenyl)-Piperazine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.