Description

Methyl 3-Amino-4-(4-Methylpiperazin-1-Yl)Benzoate is a high-purity, advanced pharmaceutical intermediate featuring a benzoate ester core substituted with amino and methylpiperazinyl groups. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex organic molecules in custom synthesis and process development.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies in organic synthesis and medicinal chemistry.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	Methyl 3-Amino-4-(4-Methylpiperazin-1-Yl)Benzoate
CAS No.	65639-61-4
Molecular Formula	C13H19N3O2
Molecular Weight	249.31 g/mol
Synonyms	Methyl 3-amino-4-(4-methyl-1-piperazinyl)benzoate; Benzoic acid, 3-amino-4-(4-methyl-1-piperazinyl)-, methyl ester; 3-Amino-4-(4-methylpiperazin-1-yl)methyl benzoate; Methyl 3-amino-4-(N-methylpiperazino)benzoate; 65639-61-4; Methyl 3-Amino-4-(4-Methylpiperazinyl)Benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Amino-4-(4-Methylpiperazin-1-Yl)Benzoate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support compliance with cGMP, ISO, and relevant regulatory frameworks for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.