Description

3,4,5,6,7,8,9,10,11,12,13,14-Dodecahydro-18,18A-Dihydroxy-2-Methyl-2H-1-Benzoxacyclohexadecin-16(18Ah)-One is a complex macrolide-derived chemical intermediate with significant synthetic utility. This compound is valued for its intricate polycyclic structure, which serves as a versatile scaffold for advanced chemical synthesis and research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel macrolide antibiotics and other complex therapeutic agents.
• Organic Synthesis Research: Advanced scaffold for methodological studies in total synthesis, cyclization reactions, and stereochemistry.
• Fine Chemical Production: Precursor for the manufacture of specialty chemicals, flavors, and fragrances requiring complex ring systems.
• Academic & Industrial R&D: Used in laboratories for investigating structure-activity relationships (SAR) and developing new catalytic processes.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical chemistry.

Basic Information

Product Name	3,4,5,6,7,8,9,10,11,12,13,14-Dodecahydro-18,18A-Dihydroxy-2-Methyl-2H-1-Benzoxacyclohexadecin-16(18Ah)-One
CAS No.	65580-01-0
Molecular Formula	C22H38O4
Molecular Weight	366.54 g/mol
Synonyms	2H-1-Benzoxacyclohexadecin-16(18Ah)-one, 3,4,5,6,7,8,9,10,11,12,13,14-dodecahydro-18,18a-dihydroxy-2-methyl-; 18,18a-Dihydroxy-2-methyl-3,4,5,6,7,8,9,10,11,12,13,14-dodecahydro-2H-1-benzoxacyclohexadecin-16(18aH)-one; (18aR)-18,18a-Dihydroxy-2-methyl-3,4,5,6,7,8,9,10,11,12,13,14-dodecahydro-2H-1-benzoxacyclohexadecin-16(18aH)-one; Aplasmomycin hydroquinone derivative; Macrolide intermediate 65580-01-0
EINECS	Contact for details

Quality Control

Our production of 3,4,5,6,7,8,9,10,11,12,13,14-Dodecahydro-18,18A-Dihydroxy-2-Methyl-2H-1-Benzoxacyclohexadecin-16(18Ah)-One (CAS 65580-01-0) adheres to stringent in-process controls and final release testing. Each batch is characterized and verified using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere or with desiccant for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.