Description

2,5-Piperazinedione,3-Methyl-6-Methylene-,(S)-(9Ci) is a specialized chiral piperazinedione derivative, a key structural motif in medicinal chemistry. This compound matters as a versatile synthetic intermediate for constructing complex molecules, particularly in the development of novel pharmaceuticals and bioactive compounds. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of peptide mimetics, enzyme inhibitors, and other high-value fine chemicals. The product is supplied under CAS No. 65519-18-8.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways.
• Peptidomimetic Research: Used in the design and synthesis of peptidomimetics, which are molecules that mimic the structure and function of peptides but with improved stability and bioavailability.
• Protease Inhibitor Development: Serves as a core scaffold in the research and development of protease inhibitors, a major class of therapeutic agents.
• Asymmetric Synthesis: Utilized in chiral synthesis due to its defined (S)-configuration, enabling the construction of enantiomerically pure compounds.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Academic & Contract Research: A valuable reagent for academic research and contract research organizations (CROs) focused on organic and medicinal chemistry.

Basic Information

Product Name	2,5-Piperazinedione,3-Methyl-6-Methylene-,(S)-(9Ci)
CAS No.	65519-18-8
Molecular Formula	C7H10N2O2
Molecular Weight	154.17 g/mol
Synonyms	(S)-3-Methyl-6-methylenepiperazine-2,5-dione; (S)-3-Methyl-6-methylenepiperazine-2,5-dione; 3-Methyl-6-methylenepiperazine-2,5-dione, (S)-; (S)-3-Methyl-6-methylenepiperazinedione; (S)-Dehydro-3-methylpiperazine-2,5-dione; (S)-3-Methyl-6-methylenepiperazine-2,5-dione (9CI); 2,5-Piperazinedione, 3-methyl-6-methylene-, (S)-; (S)-3-Methyl-6-methylenepiperazine-2,5-dione
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione,3-Methyl-6-Methylene-,(S)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.