Description

Poly (L-Lactide-Co-E-Caprolactone) is a biodegradable, biocompatible copolymer synthesized from L-lactide and ε-caprolactone monomers. This material is engineered to offer a unique balance of mechanical properties and controlled degradation rates, making it a critical component in advanced medical and pharmaceutical applications. It is primarily sought after by manufacturers in the biomedical, pharmaceutical, and controlled-release agrochemical sectors for developing next-generation implantable devices and drug delivery systems.

Application

• Biomedical Implants: Used as a resorbable material for surgical sutures, bone fixation devices (screws, pins), and tissue engineering scaffolds.
• Drug Delivery Systems: A key polymer for formulating controlled-release microspheres, nanoparticles, and injectable depots for sustained pharmaceutical action.
• Tissue Engineering: Serves as a biodegradable matrix or scaffold to support cell growth and tissue regeneration in regenerative medicine.
• Medical Adhesives & Sealants: Formulated into bioresorbable surgical glues and sealants for wound closure and hemostasis.
• Cosmetic & Dermatology: Employed in long-lasting dermal fillers and subdermal implants due to its biocompatibility and predictable absorption profile.
• Agrochemical Delivery: Utilized in advanced formulations for the slow, controlled release of pesticides or fertilizers.

Basic Information

Product Name	Poly (L-Lactide-Co-E-Caprolactone)
CAS No.	65408-67-5
Molecular Formula	(C3H4O2)m-(C6H10O2)n
Molecular Weight	Varies by lactide:caprolactone ratio and polymerization degree. Contact for details.
Synonyms	Poly(L-lactide-co-ε-caprolactone); PLCL; Poly(L-lactic acid-co-ε-caprolactone); Poly(LLA-co-CL); Resomer® LC (series); P(LA-co-CL); Lactide-Caprolactone Copolymer; Biodegradable Polyester Copolymer
EINECS	Contact for details.

Quality Control

Our Poly (L-Lactide-Co-E-Caprolactone) is manufactured under strict quality management systems. Each batch undergoes rigorous testing for critical parameters including monomer ratio, molecular weight, polydispersity, and residual solvents to ensure consistency and performance. Certificates of Analysis (COA) detailing specifications and test results are provided with every shipment. Production can be aligned with cGMP guidelines for pharmaceutical and medical device applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at temperatures between 2°C and 8°C for long-term stability, or at controlled room temperature (15-25°C) for short-term use. This polymer is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent hydrolysis and molecular weight degradation.

Specification

Item	Specification
Appearance	White to off-white powder or granules
Identification (IR)	Conforms to structure
Lactide:Caprolactone Ratio	50:50, 70:30, 85:15, or custom
Inherent Viscosity (dl/g)	1.0 - 4.0 (or as per grade)
Glass Transition Temp (Tg)	-10°C to 40°C (grade-dependent)
Residual Monomers	< 0.5% (by HPLC)
Residual Solvents	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.