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1,2-Dioleoyl-3-Palmitoyl-Rac-Glycerol CAS NO 65390-75-2


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CAS No.:65390-75-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Dioleoyl-3-palmitoyl-rac-glycerol is a structured triglyceride (TAG) composed of two oleic acid and one palmitic acid residues on a glycerol backbone. This specific fatty acid configuration is critical for applications requiring a defined lipid matrix with particular melting and crystallization behaviors. It is a key intermediate and reference standard for research and development in advanced lipid science. Target industries include pharmaceutical development, nutritional science, and specialty chemical manufacturing for high-value applications.

Application

  • Pharmaceutical Excipient & Drug Delivery: Used as a structured lipid component in lipid-based drug delivery systems (LBDDS), including self-emulsifying drug delivery systems (SEDDS) and solid lipid nanoparticles (SLNs), to enhance bioavailability of poorly soluble active pharmaceutical ingredients (APIs).
  • Biochemical & Nutritional Research: Serves as a critical reference standard and substrate in studies of lipid metabolism, lipase specificity, and the synthesis of structured lipids for infant formula and medical nutrition.
  • Cosmetic & Personal Care Formulations: Acts as an emollient and skin-conditioning agent in high-end cosmetic products, leveraging its specific fatty acid profile to improve texture and stability.
  • Chemical Synthesis Intermediate: Employed as a building block for the synthesis of more complex lipids, phospholipids, and other ester derivatives in fine chemical production.
  • Analytical Standard: Essential for the calibration and validation of analytical methods such as Gas Chromatography (GC) and High-Performance Liquid Chromatography (HPLC) in quality control laboratories.

Basic Information

Product Name 1,2-Dioleoyl-3-palmitoyl-rac-glycerol
CAS No. 65390-75-2
Molecular Formula C55H102O6
Molecular Weight 859.41 g/mol
Synonyms 1,2-Dioleoyl-3-palmitoyl-sn-glycerol; OOP; TAG 18:1/18:1/16:0; Glycerol 1,2-dioleate 3-palmitate; rac-1,2-Dioleoyl-3-palmitoylglycerol; Triacylglycerol OOP; 1,2-Di-O-oleoyl-3-O-palmitoyl-rac-glycerol; (9Z,9'Z)-1,2-bis(octadec-9-enoyloxy)-3-(hexadecanoyloxy)propane
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Quality Control

Our 1,2-Dioleoyl-3-palmitoyl-rac-glycerol is produced under strict quality management protocols. Each batch is characterized using advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic profiles. While not certified as a pharmaceutical active ingredient, our production can align with cGMP principles for research and development purposes upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture absorption. Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance Colorless to pale yellow viscous oil or solid
Identification (HPLC/GC) Conforms
Purity (HPLC Area %) ≥ 95.0%
Acid Value ≤ 1.0 mg KOH/g
Peroxide Value ≤ 5.0 meq/kg
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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