Description

n-[2-(4-Methoxybenzhydryloxy)Ethyl]-N'-[3-(4-Fluorobenzoyl)Propyl]Piperazine Dimaleate is a high-purity pharmaceutical intermediate and research chemical. This compound is critical for the synthesis and development of advanced therapeutic agents, particularly in the central nervous system (CNS) and neuropharmacology domains. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for neurological and psychiatric drug candidates.
• Research & Development: Used as a reference standard and precursor in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Preclinical Studies: Serves as a critical material in pharmacological and toxicological evaluations during early-stage drug development.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce complex piperazine and benzoyl functionalities into target molecules.
• Academic Research: Utilized in university and institutional labs for studying receptor-ligand interactions and developing new synthetic methodologies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	n-[2-(4-Methoxybenzhydryloxy)Ethyl]-N'-[3-(4-Fluorobenzoyl)Propyl]Piperazine Dimaleate
CAS No.	65329-80-8
Molecular Formula	C35H39FN2O7 • C4H4O4
Molecular Weight	698.75 g/mol
Synonyms	1-[2-[(4-Methoxyphenyl)phenylmethoxy]ethyl]-4-[3-(4-fluorobenzoyl)propyl]piperazine dimaleate; 1-[2-[(4-Methoxyphenyl)diphenylmethoxy]ethyl]-4-[3-(4-fluorobenzoyl)propyl]piperazine maleate (1:2); N-[2-(4-Methoxybenzhydryloxy)ethyl]-N'-[3-(4-fluorobenzoyl)propyl]piperazine dimaleate; Piperazine, 1-[2-[(4-methoxyphenyl)phenylmethoxy]ethyl]-4-[3-(4-fluorobenzoyl)propyl]-, (2Z)-2-butenedioate (1:2); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our n-[2-(4-Methoxybenzhydryloxy)Ethyl]-N'-[3-(4-Fluorobenzoyl)Propyl]Piperazine Dimaleate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure compliance with stringent industry standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.