Description

5,6-Dimethoxysterigmatocystin is a chemically modified derivative of the mycotoxin sterigmatocystin, characterized by the addition of methoxy groups at the 5 and 6 positions. This compound is of significant interest in biochemical and pharmaceutical research, particularly as a reference standard and a key intermediate in the study of aflatoxin biosynthesis pathways. It serves as a critical tool for researchers and quality control laboratories in the life sciences sector, enabling precise analytical work and method development.

Application

• Analytical Reference Standard: Primary use as a high-purity certified standard for the calibration of equipment and validation of analytical methods (e.g., HPLC, LC-MS) in mycotoxin testing.
• Biochemical Research: Investigation of the enzymatic pathways involved in aflatoxin and sterigmatocystin biosynthesis in fungi like Aspergillus species.
• Toxicology Studies: Utilized in in vitro and in vivo studies to understand the metabolic activation, toxicity profile, and potential mutagenic effects of sterigmatocystin derivatives.
• Pharmaceutical Impurity Profiling: Acts as a known impurity or metabolite standard in the development and quality control of pharmaceuticals derived from fungal fermentation processes.
• Food and Feed Safety: Supports research and monitoring programs aimed at detecting and quantifying sterigmatocystin-related contaminants in agricultural commodities.
• Method Development: Essential for developing and optimizing new chromatographic and spectroscopic techniques for the detection of complex mycotoxins.

Basic Information

Product Name	5,6-Dimethoxysterigmatocystin
CAS No.	65176-75-2
Molecular Formula	C20H18O8
Molecular Weight	386.35 g/mol
Synonyms	5,6-Dimethoxy-sterigmatocystin; Sterigmatocystin, 5,6-dimethoxy-; 5,6-Dimethoxysterigmatocystine; 2,3,6a,9a-Tetrahydro-4-methoxy-3,6a,9a-trimethyl-9H-furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,7,8,11-tetrone, 5,6-Dimethoxy Derivative
EINECS	Contact for details

Quality Control

Every batch of our 5,6-Dimethoxysterigmatocystin is produced and handled under strict quality management protocols. The material undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the exacting standards required for research and analytical applications. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystals
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.