Description

Lolitrem C is a potent indole-diterpene mycotoxin produced by specific endophytic fungi. This compound is of significant interest in veterinary and agricultural research due to its role as a primary causative agent of ryegrass staggers, a neurological disorder in grazing livestock. Researchers and analytical laboratories require high-purity standards for toxicological studies, reference material production, and the development of diagnostic assays. Lolitrem C CAS NO 109862-63-7 is supplied as a high-grade material suitable for these demanding applications.

Application

• Veterinary Toxicology Research: Used as a certified reference standard to study the pathophysiology, diagnosis, and treatment of ryegrass staggers in cattle, sheep, and other livestock.
• Agricultural Science: Employed in research to understand fungal-plant interactions, assess the risk of endophyte-infected pastures, and develop management strategies for livestock safety.
• Analytical Method Development: Serves as a critical calibration standard for developing and validating sensitive detection methods, such as HPLC-MS/MS, for mycotoxin screening in forage and feed.
• Phytochemical Reference: Used as a high-purity chemical marker in the isolation, identification, and quantification of related indole-diterpenes in complex biological matrices.
• Biosynthesis Studies: Utilized in biochemical research to elucidate the biosynthetic pathways of tremorgenic mycotoxins in fungi.

Basic Information

Product Name	Lolitrem C
CAS No.	109862-63-7
Molecular Formula	C₄₂H₅₅NO₇
Molecular Weight	685.9 g/mol
Synonyms	Lolitrem C; Lolitriol; 1H-Indole-3-methanol, 2,3,4,4a,5,6,7,8,8a,9,10,10a-dodecah-10a-hydroxy-4a,8-dimethyl-6-methylene-2-oxo-9-[(2E)-2-methyl-2-butenoyl]oxy]-, (4aS,8S,8aS,9S,10aS)-
EINECS	Contact for details

Quality Control

Every batch of Lolitrem C is produced and analyzed under strict quality protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards for reference materials. Comprehensive analysis includes identification by spectroscopic methods and quantitative purity determination by HPLC. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and ensure long-term stability. Allow the container to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.