Description

3-Chloro-4-Fluorobenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 3-chloro-4-fluorobenzoyl moiety, a privileged structural motif in medicinal chemistry. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially in kinase inhibitor and antibiotic research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized fluorinated aromatic compounds used in electronic displays.
• Polymer Chemistry: Acts as a monomer or modifying agent for creating high-performance, specialty polymers and resins.
• Peptide Coupling Reagent: Facilitates amide bond formation in complex peptide and protein synthesis.
• Dye & Pigment Manufacturing: Intermediate for producing fluorinated dyes and pigments with enhanced properties.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and creating compound libraries.

Basic Information

Product Name	3-Chloro-4-Fluorobenzoyl Chloride
CAS No.	65055-17-6
Molecular Formula	C7H3Cl2FO
Molecular Weight	193.00 g/mol
Synonyms	3-Chloro-4-fluorobenzoic acid chloride; 4-Fluoro-3-chlorobenzoyl chloride; 3-Chloro-4-fluorobenzoic acid chloride; Benzoic acid, 3-chloro-4-fluoro-, chloride; 3-Chloro-4-fluorobenzoyl chloride; 65055-17-6; 3-Chloro-4-fluoro-benzoyl chloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluorobenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent decomposition. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.