Description

3Alpha-Hydroxy-5Beta-Cholan-24-Oic Acid 3-Sulfate Disodium Salt Hydrate is a high-purity, water-soluble bile acid derivative. This compound is a critical biochemical reagent and synthetic intermediate valued for its defined structure and consistent performance. It is primarily utilized by research institutions and pharmaceutical companies engaged in metabolic studies, hepatobiliary research, and the development of diagnostic assays.

Application

• Biochemical Research: Used as a reference standard and substrate in studies of bile acid metabolism, liver function, and cholestatic diseases.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of more complex therapeutic agents targeting nuclear receptors like FXR (Farnesoid X Receptor).
• Diagnostic Reagents: Employed in the calibration and development of in-vitro diagnostic (IVD) kits for quantifying bile acid levels in clinical samples.
• Cell Culture & Physiology: Applied in cell-based assays to investigate the effects of sulfated bile acids on cellular signaling and membrane transport.
• Analytical Standards: Essential for High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) method development and validation in bioanalytical laboratories.

Basic Information

Product Name	3Alpha-Hydroxy-5Beta-Cholan-24-Oic Acid 3-Sulfate Disodium Salt Hydrate
CAS No.	64936-81-8
Molecular Formula	C24H37Na2O8S • xH2O
Molecular Weight	Anhydrous: 530.58 g/mol (Contact for exact hydrate form weight)
Synonyms	Lithocholic Acid 3-Sulfate Disodium Salt; 3α-Sulfolithocholyltaurine Disodium Salt Precursor; 3α-Hydroxy-5β-cholan-24-oic Acid 3-(Hydrogen Sulfate) Disodium Salt; Sodium 3α-Sulfolithocholate; Disodium 3α-Sulfo-5β-cholan-24-oate; Taurolithocholic Acid 3-Sulfate Disodium Salt Related Compound; 5β-Cholan-24-oic Acid, 3α-hydroxy-, 3-sulfate, disodium salt
EINECS	Contact for details

Quality Control

Our 3Alpha-Hydroxy-5Beta-Cholan-24-Oic Acid 3-Sulfate Disodium Salt Hydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 10.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.