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(7R,8S)-7'-Deoxo-2'-Deoxy-2',3':7,8-Bisoxy-7',5'-(Ethane-1,1-Diyloxy)Verrucarin A CAS NO 64687-84-9
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CAS No.:64687-84-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(7R,8S)-7'-Deoxo-2'-Deoxy-2',3':7,8-Bisoxy-7',5'-(Ethane-1,1-Diyloxy)Verrucarin A is a structurally complex macrocyclic trichothecene derivative, a class of compounds known for potent biological activity. This compound is of significant interest for advanced research and development in pharmacology and biochemistry, particularly in the study of eukaryotic protein synthesis inhibition. It serves as a critical reference standard and a valuable synthetic intermediate for researchers in pharmaceutical discovery, toxicology, and chemical biology.
Application
- Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of trichothecene compounds in research and quality control laboratories.
- Biochemical Research: Employed as a potent tool compound to study mechanisms of protein synthesis inhibition in eukaryotic cells.
- Chemical Synthesis: Serves as a key intermediate or precursor for the synthesis of novel trichothecene analogs with potential therapeutic applications.
- Toxicology Studies: Utilized in research to understand the toxicological profile and structure-activity relationships (SAR) of macrocyclic trichothecenes.
- Academic Research: A valuable compound for universities and research institutes focusing on natural product chemistry, mycotoxicology, and medicinal chemistry.
Basic Information
| Product Name | (7R,8S)-7'-Deoxo-2'-Deoxy-2',3':7,8-Bisoxy-7',5'-(Ethane-1,1-Diyloxy)Verrucarin A |
| CAS No. | 64687-84-9 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | 7'-Deoxo-2'-deoxy-2',3':7,8-bisoxy-7',5'-(ethane-1,1-diyloxy)verrucarin A; Verrucarin A derivative; Macrocyclic trichothecene derivative; (7R,8S)-isomer of 7'-deoxo-2'-deoxyverrucarin A bis-acetal |
| EINECS | Contact for details |
Quality Control
Every batch of (7R,8S)-7'-Deoxo-2'-Deoxy-2',3':7,8-Bisoxy-7',5'-(Ethane-1,1-Diyloxy)Verrucarin A is produced and handled under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your research and compliance needs.
Storage
Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. Keep the container sealed to protect from moisture.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content | ≤ 1.0% |
| Residual Solvents | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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