Description

n-(2'-(R)-Hydroxylignoceroyl)-D-Erythro-Sphingosine is a high-purity, synthetic sphingolipid derivative, a critical building block for advanced biochemical research and pharmaceutical development. This compound is essential for studying cell membrane structure, signal transduction pathways, and lipid metabolism. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and cosmetic industries for developing novel therapeutics and high-performance biomaterials.

Application

• Biochemical Research: A key standard and precursor for investigating sphingolipid biology, ceramide synthesis, and apoptosis signaling pathways.
• Pharmaceutical Development: Used in the synthesis of novel drug candidates targeting cancer, inflammatory diseases, and neurological disorders.
• Lipidomics & Analytical Standards: Serves as a critical reference standard for mass spectrometry and chromatography in lipid profiling studies.
• Cosmetic Science: Incorporated into advanced skincare formulations for its potential role in skin barrier function and ceramide-replenishing properties.
• Cell Culture & Media Supplements: Used as a defined lipid supplement in specialized cell culture systems to study lipid-mediated cellular processes.
• Enzyme Substrate Studies: Acts as a substrate for enzymes like ceramidases and sphingomyelin synthases in kinetic and mechanistic studies.

Basic Information

Product Name	n-(2'-(R)-Hydroxylignoceroyl)-D-Erythro-Sphingosine
CAS No.	64655-47-6
Molecular Formula	C46H91NO5
Molecular Weight	738.2 g/mol
Synonyms	N-[(2R)-2-Hydroxytetracosanoyl]-D-erythro-sphingosine; C24 α-Hydroxy Ceramide (d18:1/24:0(OH)); (2S,3R,4E)-2-[(2R)-2-Hydroxytetracosanoylamino]-4-octadecene-1,3-diol; D-erythro-Sphingosine, N-[(2R)-2-hydroxytetracosanoyl]-; Hydroxylignoceroyl Sphingosine; α-Hydroxy-N-lignoceroyl-D-erythro-sphingosine; Ceramide NS 24:0; (2R)-N-[(2S,3R,4E)-1,3-Dihydroxyoctadec-4-en-2-yl]-2-hydroxytetracosanamide
EINECS	Contact for details

Quality Control

Our n-(2'-(R)-Hydroxylignoceroyl)-D-Erythro-Sphingosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, desiccate to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.