Description

(1Ar,4E,5As,8S,8As,10S,10As)-10-Acetoxy-1A,3,5A,8,8A,9,10,10A-Octahydro-4,8,10A-Trimethyloxireno[5,6]Cyclodeca[1,2-B]Furan-7(2H)-One is a complex, high-purity sesquiterpene lactone derivative with a unique oxireno-fused cyclodecane structure. This compound is valued for its intricate molecular architecture, making it a critical advanced intermediate or reference standard in specialized organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of complex natural product analogs and potential drug candidates.
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of related sesquiterpene compounds.
• Organic Synthesis Research: Employed in academic and industrial research to study novel cycloaddition reactions and ring transformations.
• Agrochemical Development: Investigated as a precursor for novel bioactive molecules with potential pesticidal or herbicidal activity.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Item	Detail
Product Name	(1Ar,4E,5As,8S,8As,10S,10As)-10-Acetoxy-1A,3,5A,8,8A,9,10,10A-Octahydro-4,8,10A-Trimethyloxireno[5,6]Cyclodeca[1,2-B]Furan-7(2H)-One
CAS No.	64562-24-9
Molecular Formula	C20H26O5
Molecular Weight	346.42 g/mol
Synonyms	10-Acetoxy-4,8,10a-trimethyl-1a,3,5a,8,8a,9,10,10a-octahydrooxireno[5,6]cyclodeca[1,2-b]furan-7(2H)-one; 10-Acetoxy-4,8,10a-trimethyl-1a,2,3,5a,8,8a,9,10,10a,10b-decahydrooxireno[5,6]cyclodeca[1,2-b]furan-7-one; Parthenolide 10-acetate derivative; Oxireno[5,6]cyclodeca[1,2-b]furan-7(2H)-one, 10-(acetyloxy)-1a,2,3,5a,8,8a,9,10,10a,10b-decahydro-4,8,10a-trimethyl-, [1aR-(1aR*,4E,5aS*,8S*,8aS*,10S*,10aS*,10bR*)]-; Sesquiterpene lactone acetate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR to ensure structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profile is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.