Description

trans-2,3-Dihydro-3-Hydroxyeuparin CAS NO 64185-57-5 is a specific dihydroxy derivative of the natural coumarin euparin, representing a high-purity synthetic intermediate of significant interest in advanced organic synthesis. This compound is valued for its defined stereochemistry and functional groups, which make it a versatile building block for creating more complex molecular architectures. It is primarily sought by research institutions and pharmaceutical developers for applications in medicinal chemistry and as a reference standard in analytical studies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting inflammation or metabolic pathways.
• Medicinal Chemistry Research: Used as a scaffold or precursor in structure-activity relationship (SAR) studies to explore new therapeutic agents.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, or NMR for the quantification and identification of related compounds in complex mixtures.
• Biochemical Research: Investigated for its potential biological activity and interaction with various enzymes or cellular receptors in vitro.
• Organic Synthesis: Utilized as a specialized starting material or intermediate for the synthesis of more complex natural product analogs and fine chemicals.

Basic Information

Product Name	trans-2,3-Dihydro-3-Hydroxyeuparin
CAS No.	64185-57-5
Molecular Formula	C13H12O5
Molecular Weight	248.23 g/mol
Synonyms	(3R,4R)-3,4-Dihydro-3,8-dihydroxy-6-methoxy-3-methyl-1H-2-benzopyran-1-one; 3,4-Dihydro-3,8-dihydroxy-6-methoxy-3-methyl-1H-2-benzopyran-1-one; trans-3,4-Dihydro-3,8-dihydroxy-6-methoxy-3-methylisocoumarin; Dihydroxyeuparin; 3-Hydroxyeuparin derivative; Euparin dihydroxy derivative
EINECS	Contact for details

Quality Control

Every batch of trans-2,3-Dihydro-3-Hydroxyeuparin is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term stability is required.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.