Description

3-Pyridinecarbonyl Chloride, 4,5-Dimethyl- (9Ci) is a versatile and reactive heterocyclic acid chloride derivative. This compound serves as a critical building block in advanced organic synthesis, enabling the efficient introduction of the 4,5-dimethylnicotinoyl moiety. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers or organic electronic materials where the pyridine core imparts specific electronic properties.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) companies producing bespoke compounds for clients.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 4,5-Dimethyl- (9Ci)
CAS No.	64172-73-2
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	4,5-Dimethylnicotinoyl chloride; 4,5-Dimethylpyridine-3-carbonyl chloride; 3-Carbamoyl-4,5-dimethylpyridine hydrochloride (related); 4,5-Dimethyl-3-pyridinecarbonyl chloride; 4,5-Dimethylnicotinic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarbonyl Chloride, 4,5-Dimethyl- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your research and development processes. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC or titration), identity (by IR and NMR), and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain product integrity. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.