Description

3-Fluorobenzylmagnesium Chloride is a versatile organometallic reagent, specifically a Grignard reagent, essential for introducing the 3-fluorobenzyl moiety into target molecules. Its value lies in enabling efficient carbon-carbon bond formation, a critical step in synthesizing complex intermediates for advanced materials and pharmaceuticals. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing fluorinated aromatic scaffolds.

Application

• Key intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic rings.
• Building block for agrochemicals, where the fluorine atom can enhance biological activity and metabolic stability.
• Precursor in material science for creating fluorinated liquid crystals, polymers, and electronic materials.
• Reagent for organic synthesis in academic and industrial R&D laboratories for novel compound library generation.
• Used in cross-coupling reactions and nucleophilic addition reactions to carbonyl compounds.

Basic Information

Product Name	3-Fluorobenzylmagnesium Chloride
CAS No.	64168-34-9
Molecular Formula	C7H6ClFMg
Molecular Weight	168.87 g/mol
Synonyms	(3-Fluorophenyl)methylmagnesium Chloride; 3-Fluorobenzylmagnesium Chloride solution; m-Fluorobenzylmagnesium Chloride; Magnesium, chlorido[(3-fluorophenyl)methyl]-; Grignard reagent 3-FluorobenzylMgCl
EINECS	Contact for details

Quality Control

Our 3-Fluorobenzylmagnesium Chloride is produced under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing concentration, purity, and impurity profile. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This material is highly volatile and easily oxidized; it must be handled and stored using strict anhydrous and air-free techniques. Keep away from heat, sparks, open flames, and incompatible materials such as water, acids, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear solution, typically in THF or diethyl ether
Concentration	0.5 M to 2.0 M in solvent (custom concentrations available)
Assay (Titration)	≥ 95% (as Grignard reagent)
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.