Description

Ro 04-5595 Hydrochloride is a high-purity organic salt compound, primarily utilized as a key intermediate in advanced pharmaceutical research and development. Its significance lies in enabling the synthesis of novel therapeutic agents, particularly within the fields of neurology and metabolic disease research. This material is essential for pharmaceutical companies, biotechnology research institutions, and contract development and manufacturing organizations (CDMOs) engaged in the creation of new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical studies.
• Neurological Research: Used in the development of compounds targeting specific neurological pathways and receptors.
• Metabolic Disorder Studies: Applied as a precursor in research focused on metabolic regulation and related therapeutic interventions.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Can be supplied as a qualified reference standard for analytical method development and validation in quality control laboratories.
• Biochemical Research: Employed in biochemical assays to study enzyme interactions and cellular mechanisms.

Basic Information

Product Name	Ro 04-5595 Hydrochloride
CAS No.	64047-73-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ro-04-5595 HCl; Ro 04-5595 HCl; 4-(4-Chlorophenyl)-1,2,3,6-tetrahydro-1-(3-phenylpropyl)pyridine hydrochloride; 4-(4-Chlorophenyl)-1-(3-phenylpropyl)-1,2,3,6-tetrahydropyridine hydrochloride; 1-(3-Phenylpropyl)-4-(p-chlorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride; GBR-12909 Hydrochloride (Note: GBR-12909 is a closely related dopamine reuptake inhibitor; verify exact structural equivalence); Dopamine Reuptake Inhibitor (Chemical Class)
EINECS	Contact for details

Quality Control

Our Ro 04-5595 Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.