Description

4,4'-Methylenebis(Piperazine-1-Carboxylic Acid Ethyl) Ester is a specialized organic compound with a symmetrical bis-piperazine structure. This high-purity intermediate is valued for its role as a versatile building block in advanced chemical synthesis, offering reliable performance and consistent quality. It is primarily sought by manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a rigid, symmetrical linker.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with enhanced thermal and mechanical properties.
• Ligand and Catalyst Development: Utilized in the preparation of complex ligands for metal-organic frameworks (MOFs) or homogeneous catalysis.
• Research & Development: An important reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, complex organic compounds.

Basic Information

Product Name	4,4'-Methylenebis(Piperazine-1-Carboxylic Acid Ethyl) Ester
CAS No.	63981-46-4
Molecular Formula	C17H30N4O4
Molecular Weight	354.45 g/mol
Synonyms	1,1'-Methylenebis(4-ethoxycarbonylpiperazine); Ethyl 4,4'-Methylenedipiperidine-1-carboxylate; Bis(4-ethoxycarbonylpiperazin-1-yl)methane; 4,4'-Methylenebis(1-piperazinecarboxylic Acid Ethyl Ester); 1,1'-(Methylenedi-4,1-piperazinediyl)bis[ethanone] (obsolete); Methylene Bis(piperazine-1-carboxylate) Ethyl Ester; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 4,4'-Methylenebis(Piperazine-1-Carboxylic Acid Ethyl) Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure it meets the high-purity standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.