Description

3-Hydroxy-5,5,5-Trifluoro-4-(Trifluoromethyl)Valeric Acid is a high-value, fluorinated organic acid building block characterized by its unique trifluoromethyl and hydroxyl functionalities. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, where its fluorine atoms impart desirable properties like metabolic stability and enhanced bioavailability. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine groups improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Modifiers: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Complex Ligand & Catalyst Development: Utilized in organometallic chemistry for creating novel ligands and catalysts used in asymmetric synthesis.
• Fluorinated Surfactant & Additive Research: Acts as a building block for specialty surfactants and performance additives with unique surface activity.

Basic Information

Product Name	3-Hydroxy-5,5,5-Trifluoro-4-(Trifluoromethyl)Valeric Acid
CAS No.	63979-48-6
Molecular Formula	C6H6F6O3
Molecular Weight	240.10 g/mol
Synonyms	5,5,5-Trifluoro-4-(trifluoromethyl)-3-hydroxypentanoic Acid; 3-Hydroxy-5,5,5-trifluoro-4-(trifluoromethyl)pentanoic Acid; 4-(Trifluoromethyl)-3-hydroxy-5,5,5-trifluorovaleric Acid; 3-Hydroxy-4,5,5,5-tetrafluoro-4-(trifluoromethyl)valeric Acid (alternative notation); HFIP-Valeric Acid Derivative; Fluorinated Hydroxy Valeric Acid; CAS 63979-48-6
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-5,5,5-Trifluoro-4-(Trifluoromethyl)Valeric Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.