Description

1-(3,4-Dimethoxybenzyl)-4-(2-Chlorophenyl)Piperazine is a high-purity, synthetic organic compound belonging to the piperazine class of chemicals. This compound serves as a critical intermediate in the research and development of novel pharmaceutical agents, particularly those targeting the central nervous system. It is essential for medicinal chemistry research, process development, and scale-up activities within the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential therapeutic compounds, especially in neurological and psychiatric drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug candidate profiles.
• Process Chemistry & Scale-Up: Serves as a standard or starting material for developing and optimizing synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Biochemical Research: Utilized in studies investigating receptor-ligand interactions and other biochemical pathways.
• Custom Synthesis: A foundational compound for the custom synthesis of more complex, proprietary molecules for clients.

Basic Information

Product Name	1-(3,4-Dimethoxybenzyl)-4-(2-Chlorophenyl)Piperazine
CAS No.	63978-29-0
Molecular Formula	C19H23ClN2O2
Molecular Weight	346.85 g/mol
Synonyms	1-[(3,4-Dimethoxyphenyl)methyl]-4-(2-chlorophenyl)piperazine; 4-(2-Chlorophenyl)-1-(3,4-dimethoxybenzyl)piperazine; 2-Chloro-1-[4-(3,4-dimethoxybenzyl)piperazin-1-yl]benzene; 1-(2-Chlorophenyl)-4-(3,4-dimethoxybenzyl)piperazine; Vericiguat Intermediate (related chemistry); Piperazine derivative CAS 63978-29-0
EINECS	Contact for details

Quality Control

Our 1-(3,4-Dimethoxybenzyl)-4-(2-Chlorophenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP-aligned research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.