Description

n-Methyllevallorphan is a synthetic opioid receptor antagonist of significant interest in advanced pharmacological research. This compound is valued for its high affinity and selectivity, making it a critical tool for studying receptor mechanisms and developing new therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialized chemical manufacturers focused on neuropharmacology and analgesic development.

Application

• Pharmacological Research: A key reference standard and active pharmaceutical ingredient (API) intermediate in the study of opioid receptor systems.
• Neuropharmacology Studies: Used to investigate the mechanisms of action, binding affinities, and functional activities at mu, kappa, and delta opioid receptors.
• Analgesic Development: Serves as a structural template or lead compound in the discovery and development of novel pain management therapeutics.
• Biochemical Assays: Employed as a selective antagonist in in vitro and in vivo assays to characterize other opioid ligands and pathways.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related substances.
• Academic & Institutional Research: Supports fundamental neuroscience and medicinal chemistry research in university and government settings.

Basic Information

Product Name	n-Methyllevallorphan
CAS No.	63868-46-2
Molecular Formula	C₂₀H₂₇NO₂
Molecular Weight	313.44 g/mol
Synonyms	N-Methyllevallorphan; (-)-N-Methyllevallorphan; Levallorphan N-methyl derivative; 17-(Cyclopropylmethyl)-6,7-didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan; Ro 1-6794; N-Methyl-levallorphan
EINECS	Contact for details

Quality Control

Our n-Methyllevallorphan is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced chromatographic and spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product should be kept under an inert atmosphere for long-term stability and handled in accordance with safe laboratory practices for potent compounds.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.