Description

Nh-Bis(Peg4-Oh) CAS NO 63721-06-2 is a specialized polyethylene glycol (PEG)-based linker or spacer molecule, featuring terminal hydroxyl groups. This compound is valued for its role in bioconjugation and polymer chemistry, providing a hydrophilic, flexible bridge to modify solubility and pharmacokinetic properties. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing drug delivery systems, diagnostic reagents, and functional polymers.

Application

• Bioconjugation Linker: Used to conjugate drugs, peptides, or imaging agents to antibodies, proteins, or nanoparticles to enhance therapeutic efficacy and targeting.
• PEGylation Reagent: Serves as a building block for creating PEGylated therapeutics to improve drug solubility, stability, and circulation time in vivo.
• Polymer Synthesis: Acts as a monomer or cross-linking agent in the synthesis of hydrogels, dendrimers, and other functional polymeric materials.
• Surface Modification: Employed to functionalize surfaces (e.g., nanoparticles, biosensors) with hydrophilic PEG layers to reduce non-specific binding and improve biocompatibility.
• Diagnostic Reagent Production: Utilized in the development of contrast agents and fluorescent probes for diagnostic imaging and assays.
• Intermediate for Further Derivatization: The terminal hydroxyl groups provide reactive sites for further chemical modification to attach various functional groups (e.g., amines, carboxylates, maleimides).

Basic Information

Product Name	Nh-Bis(Peg4-Oh)
CAS No.	63721-06-2
Molecular Formula	C18H38O10
Molecular Weight	414.49 g/mol
Synonyms	1,11-Bis(2,5,8,11-tetraoxadodecan-12-yloxy)-3,6,9-trioxaundecane; 2,2'-(Ethylenedioxyl)bis(ethanol), tetraethylene glycol derivative; PEG4-based bis-hydroxyl linker; Tetraethylene glycol-based diol spacer; NH(PEG4-OH)2; Bis(PEG4-alcohol); 1,1'-[1,2-ethanediylbis(oxy-2,1-ethanediyloxy-2,1-ethanediyloxy-2,1-ethanediyloxy)]bis-2-ethanol
EINECS	Contact for details

Quality Control

Our Nh-Bis(Peg4-Oh) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect product quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.