Description

(5R,6S)-3-[[2-(Acetylamino)Ethyl]Thio]-6-[(R)-1-Hydroxyethyl]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid CAS NO 63701-32-6 is a high-purity, advanced pharmaceutical intermediate belonging to the carbapenem class of β-lactam antibiotics. This compound is critical for the research, development, and synthesis of novel antibacterial agents, offering a key structural scaffold for creating potent and broad-spectrum therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on combating antibiotic-resistant bacterial infections.

Application

• Key Intermediate for Carbapenem Antibiotics: Serves as a crucial building block in the multi-step synthesis of potent carbapenem drugs like meropenem, ertapenem, and doripenem.
• Pharmaceutical Research & Development (R&D): Used in medicinal chemistry programs to develop new generations of β-lactam antibiotics with improved efficacy and resistance profiles.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes and scaling up production processes for active pharmaceutical ingredients (APIs) in GMP environments.
• Academic & Biochemical Studies: Utilized in university and institutional research to study the structure-activity relationships (SAR) and mechanism of action of β-lactam compounds.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.

Basic Information

Product Name	(5R,6S)-3-[[2-(Acetylamino)Ethyl]Thio]-6-[(R)-1-Hydroxyethyl]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid
CAS No.	63701-32-6
Molecular Formula	C13H18N2O5S
Molecular Weight	314.36 g/mol
Synonyms	(5R,6S)-3-[(2-Acetamidoethyl)thio]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; (5R,6S)-3-[(2-Acetamidoethyl)thio]-6-[(R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; Meropenem Intermediate; Carbapenem Derivative; 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[2-(acetylamino)ethyl]thio]-6-[(1R)-1-hydroxyethyl]-7-oxo-, (5R,6S)-; 63701-32-6
EINECS	Contact for details

Quality Control

Our (5R,6S)-3-[[2-(Acetylamino)Ethyl]Thio]-6-[(R)-1-Hydroxyethyl]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and comprehensive identification tests, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.